Free Clinical Pathology practice for NEET PG and INI-CET Pathology, with a written explanation on every question.
11 questions · Free explanations
Showing 1–11 of 11 questions
Q1 · Immunohistochemistry
NEET PGHardExplanation
S-100 and HMB-45 mark melanocytic tumours. CD20 marks B cells, desmin marks muscle and cytokeratin marks epithelial or carcinoma cells. Immunohistochemistry helps classify poorly differentiated tumours.
Q2 · CSF Analysis
NEET PGMediumExplanation
Bacterial meningitis gives a neutrophilic pleocytosis with high protein and low glucose, as bacteria consume glucose. Viral meningitis shows lymphocytes with normal glucose, and tuberculous meningitis shows lymphocytes with very low glucose.
Q3 · Special Stains
MediumExplanation
Prussian blue, the Perls stain, colours iron and haemosiderin blue and is useful in haemochromatosis and haemosiderosis. Congo red stains amyloid, Ziehl-Neelsen stains acid-fast bacilli and PAS stains glycogen and fungi.
Q4 · Transfusion Reactions
MediumExplanation
ABO-incompatible transfusion causes a Type II hypersensitivity: preformed IgM antibodies bind donor red cells and activate complement, causing intravascular haemolysis. It is a medical emergency.
Q5 · Sickle Cell Disease
EasyExplanation
In sickle cell disease, glutamate is replaced by valine at position 6 of the beta-globin chain. Deoxygenated HbS polymerises, deforming red cells into sickles that cause vaso-occlusion and haemolysis.
Q6 · Coagulation Tests
MediumExplanation
PT assesses the extrinsic pathway and factor VII, while aPTT assesses the intrinsic pathway. Isolated PT prolongation points to factor VII deficiency or early warfarin effect, as factor VII has the shortest half-life.
Q7 · Malaria
EasyExplanation
Plasmodium falciparum shows characteristic banana or crescent-shaped gametocytes and causes the most severe disease, including cerebral malaria. It parasitises red cells of all ages, producing high parasitaemia.
Q8 · Tumour Markers
EasyExplanation
PSA is a glycoprotein produced by prostate epithelium; levels rise in prostate carcinoma and also in benign prostatic hyperplasia and prostatitis. It is used for screening, with known limitations, and to monitor treatment response.
Q9 · Thrombosis
MediumExplanation
Virchow's triad comprises endothelial injury, stasis or turbulent flow, and hypercoagulability. These factors underlie venous and arterial thrombosis and guide risk assessment for conditions such as deep vein thrombosis.
Q10 · Anaemia of Chronic Disease
HardExplanation
Anaemia of chronic disease shows low serum iron but normal or high ferritin, because hepcidin sequesters iron, together with a low TIBC. This distinguishes it from iron deficiency, where ferritin is low and TIBC is high.
Q11 · Acute Lymphoblastic Leukaemia
MediumExplanation
Acute lymphoblastic leukaemia is the commonest childhood leukaemia. Blasts are TdT positive and B-ALL commonly expresses CD10. With modern therapy the prognosis in children is generally favourable.
Clinical Pathology sits within Pathology, which carries the same syllabus in both exams. This set runs to 11 questions, each tagged Easy, Medium or Hard, 2 of them at Hard, and 2 drawn from previous-year papers.
Answer first, then read the explanation even on the ones you got right — the reasoning is where Clinical Pathology marks are actually won, and it is what separates a recalled fact from a question you can solve in a new form. Once the Easy set feels comfortable, filter to Hard to find the gaps Pathology examiners keep returning to.
FAQ
Yes. Every question and explanation in this Clinical Pathology set is free and open — no login, no form and no payment. The explanation appears the moment you answer.
Clinical Pathology sits within Pathology, which appears in the same form in both syllabuses. General and systemic pathology, from cell injury and inflammation to the tumour markers and classic morphologies that appear as image and stem questions.
No. No account, no password, no OTP. Answer in the browser and your answers stay on your device for the session.