Free General Pharmacology practice for NEET PG and INI-CET Pharmacology, with a written explanation on every question.
7 questions · Free explanations
Showing 1–7 of 7 questions
Q1 · Bioavailability
NEET PGEasyExplanation
Bioavailability is the fraction of an administered dose reaching the systemic circulation unchanged. Intravenous administration bypasses absorption entirely, so its bioavailability is defined as 100% and is the reference against which other routes are measured.
Q2 · First-pass Metabolism
NEET PGMediumExplanation
Sublingual absorption drains into the systemic circulation via the superior vena cava, bypassing the portal vein and hepatic first-pass metabolism. This is why sublingual nitroglycerin acts rapidly and reliably.
Q3 · Enzyme Kinetics
HardExplanation
Phenytoin, ethanol and high-dose aspirin follow zero-order kinetics because their metabolising enzymes saturate at therapeutic concentrations. A small dose increase can then cause a disproportionate rise in plasma level and toxicity.
Q4 · Competitive Inhibition
MediumExplanation
A competitive inhibitor competes for the active site, raising the apparent Km (lower affinity) but leaving Vmax unchanged, since the inhibition can be overcome by increasing substrate concentration.
Q5 · Receptor Types
NEET PGMediumExplanation
The insulin receptor is a receptor tyrosine kinase. Ligand binding triggers autophosphorylation of tyrosine residues, activating downstream signalling. Insulin-like growth factor and several growth factor receptors work the same way.
Q6 · Therapeutic Index
EasyExplanation
Digoxin, lithium, warfarin, phenytoin and theophylline have narrow therapeutic indices, meaning the toxic dose is close to the therapeutic dose. They require plasma level monitoring to avoid toxicity.
Q7 · Drug Half-life
HardExplanation
It takes about 4 to 5 half-lives to reach 94 to 97% of steady-state concentration, and the same number to eliminate a drug after stopping it. This principle guides dosing intervals and loading-dose decisions.
General Pharmacology sits within Pharmacology, which carries the same syllabus in both exams. This set runs to 7 questions, each tagged Easy, Medium or Hard, 2 of them at Hard, and 3 drawn from previous-year papers.
Answer first, then read the explanation even on the ones you got right — the reasoning is where General Pharmacology marks are actually won, and it is what separates a recalled fact from a question you can solve in a new form. Once the Easy set feels comfortable, filter to Hard to find the gaps Pharmacology examiners keep returning to.
FAQ
Yes. Every question and explanation in this General Pharmacology set is free and open — no login, no form and no payment. The explanation appears the moment you answer.
General Pharmacology sits within Pharmacology, which appears in the same form in both syllabuses. Drug classes, mechanisms and adverse effects. One of the highest yield subjects per hour of study, because the same drugs recur across cycles.
No. No account, no password, no OTP. Answer in the browser and your answers stay on your device for the session.